Searchable abstracts of presentations at key conferences in endocrinology

ea0012p101 | Reproduction | SFE2006

The effects of feeding an n-3 polyunsaturated fatty acid (PUFA) rich diet on ovarian function in the Welsh mountain ewe

Naddafy JM , Chin EC , Cheng Z , Brickell JS , Wathes DC , Abayasekara DRE

Polyunsaturated fatty acids (PUFA) act as precursors for prostaglandin (PG) synthesis. PGs both inhibit and stimulate ovarian steroidogenesis. We have therefore examined the hypothesis that high n-3 PUFA diets affect ovarian steroid synthesis through modulating prostaglandin synthesis.Welsh mountain ewes were individually fed a control diet or a diet containing linseed (high in n-3 PUFA) for 6 weeks. To assess the impact of the diet during differe...

ea0011p750 | Steroids | ECE2006

Dietary polyunsaturated fatty acid supplementation in vivo modulates ovine adrenal steroidogenesis in vitro

Chin EC , Naddafy JM , Cheng Z , Brickell JS , Wathes DC , Abayasekara DRE

Increased dietary intake of polyunsaturated fatty acids (PUFAs) has been reported to be associated with a decreased incidence of cardiovascular disease. Increased dietary intake of polyunsaturated fatty acids (PUFAs) has been reported to be associated with a decreased incidence of cardiovascular disease. We have recently reported that ovarian steroid synthesis in ewes fed a diet high in n-3 PUFAs is significantly compromised1. Hence in this study we have assessed th...